Whole genome sequencing analysis can provide valuable information
on the taxonomic identification of the strains and their potential
functional traits, including virulence factors, resistance to
antimicrobials, and production of toxic metabolites.
At TAXON, we have developed a proprietary tool that establishes the microbial functional profile based on genomic functions. Our genomic characterization analyses help to support risk assessment for microorganisms seeking approval from regulatory agencies such as the European Union Food Safety Authority (EU/EFSA) and the United States Food and Drug Administration (US-FDA).
Furthermore, as the genome of producer microbes constitutes the inventive part of a productive process, complete genome sequencing is required during patent applications. Finally, by linking genotype with phenotype, companies can select the most suitable microbial candidates to develop their products, relying on our microbial functional profiles.
The service offered by TAXON involves the complete characterization of microbial strains, which is essential for the development and optimization of microorganisms used in food ingredients or as production strains. This service includes complete genome-based strain characterization required for EFSA approval and claims, screening for antibiotic resistance and virulence genes, plasmid detection and identification, and gene of interest screening. TAXON has significant expertise and years of experience in this field.
Enterococcus mundtii is a rare human pathogen. In this
case, we conclude that although E. mundtii CRL1656 is
phylogenetically closer to E. faecium, frequently
responsible for nosocomial infections, this strain does not
encode the most relevant virulence factors found in the
enterococcal clinical isolates. This strain was isolated from
stripping milk cows and, given its bacteriocinogenic capacity,
it has been proposed as a probiotic microorganism to prevent
mastitis in these mammals. The circular genome representation
showed positions of protein-coding genes, foreign DNA, tRNA
genes, and putative transposases and integrases. In addition,
the encoded function in the 4 putative genomic islands found was
Reference: Repizo, G.D., Espariz, M., Blancato, V.S. et al. Genomic comparative analysis of the environmental Enterococcus mundtii against enterococcal representative species. BMC Genomics 15, 489 (2014). https://doi.org/10.1186/1471-2164-15-489
Get reliable and comprehensive genomic assembly and annotation tailored to your research needs.
Utilize whole genome sequence analysis for precise taxonomic identification of microorganisms, meeting regulatory requirements for food and production applications.
Genomic or metagenomic data are searched for genes encoding proteins with exceptional characteristics that can be used for specific industrial, agronomical, or pharmaceutical purposes.
The whole genomic sequences of various organisms are analyzed and compared through comparative genomics. This helps in determining the uniqueness of the trait of interest.
Is this what you need?