Genome Assembly and Annotation

The usual starting point for bioinformatics analyses involves genome assembly and functional annotations. Frequently, this service includes whole genome sequence identification and genomic characterization. As for genome assembly, it is the process of piecing together the short reads generated from DNA sequencing into a contiguous sequence, known as a contig. The contigs are then further merged into scaffolds, representing a more comprehensive view of the genome. This process can be quite challenging, particularly when working with complex genomes or when the sequencing depth is not sufficient. Ultimately, the quality of the assembly will depend on the combination of the sequencing technology used, the bioinformatics tools employed, and the expertise of the researchers involved.

TAXON utilizes assembly pipelines that can follow either a reference based or de novo approach, which enables the provision of a high-quality finished genome sequence. Once sequence reads have been optimally merged into finished genomes, a thorough quality assessment is conducted.

Delivered output
Assembled sequences (in FASTA and Genbank format).
A full report containing methods and assembly results including quality statistics (in pdf format).

Genomic Characterization

Identify genes responsible for desirable traits and ensure the absence of undesirable characteristics, enabling the development of safer and more efficient microorganisms.

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Comparative Genomics

The whole genomic sequences of various organisms are analyzed and compared through comparative genomics. This helps in determining the uniqueness of the trait of interest.

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